diff --git a/Marlin/src/HAL/LPC1768/inc/SanityCheck.h b/Marlin/src/HAL/LPC1768/inc/SanityCheck.h
index a6286ba6f4..46a876a836 100644
--- a/Marlin/src/HAL/LPC1768/inc/SanityCheck.h
+++ b/Marlin/src/HAL/LPC1768/inc/SanityCheck.h
@@ -144,7 +144,7 @@ static_assert(DISABLED(BAUD_RATE_GCODE), "BAUD_RATE_GCODE is not yet supported o
     #error "Serial port pins (2) conflict with Z4 pins!"
   #elif ANY_RX(2, X_DIR_PIN, Y_DIR_PIN)
     #error "Serial port pins (2) conflict with other pins!"
-  #elif Y_HOME_DIR < 0 && IS_TX2(Y_STOP_PIN)
+  #elif Y_HOME_TO_MIN && IS_TX2(Y_STOP_PIN)
     #error "Serial port pins (2) conflict with Y endstop pin!"
   #elif HAS_CUSTOM_PROBE_PIN && IS_TX2(Z_MIN_PROBE_PIN)
     #error "Serial port pins (2) conflict with probe pin!"
diff --git a/Marlin/src/feature/powerloss.cpp b/Marlin/src/feature/powerloss.cpp
index db78e7331b..a7474794de 100644
--- a/Marlin/src/feature/powerloss.cpp
+++ b/Marlin/src/feature/powerloss.cpp
@@ -375,7 +375,7 @@ void PrintJobRecovery::resume() {
 
   gcode.process_subcommands_now_P(PSTR("G92.9E0")); // Reset E to 0
 
-  #if Z_HOME_DIR > 0
+  #if Z_HOME_TO_MAX
 
     float z_now = z_raised;
 
diff --git a/Marlin/src/gcode/calibrate/G28.cpp b/Marlin/src/gcode/calibrate/G28.cpp
index 23eafe4bb6..aacfcfa42f 100644
--- a/Marlin/src/gcode/calibrate/G28.cpp
+++ b/Marlin/src/gcode/calibrate/G28.cpp
@@ -73,7 +73,7 @@
     current_position.set(0.0, 0.0);
     sync_plan_position();
 
-    const int x_axis_home_dir = x_home_dir(active_extruder);
+    const int x_axis_home_dir = TOOL_X_HOME_DIR(active_extruder);
 
     const float mlx = max_length(X_AXIS),
                 mly = max_length(Y_AXIS),
diff --git a/Marlin/src/inc/Conditionals_LCD.h b/Marlin/src/inc/Conditionals_LCD.h
index de97712a08..545ee403a1 100644
--- a/Marlin/src/inc/Conditionals_LCD.h
+++ b/Marlin/src/inc/Conditionals_LCD.h
@@ -814,6 +814,23 @@
   #endif
 #endif // FILAMENT_RUNOUT_SENSOR
 
+// Homing to Min or Max
+#if X_HOME_DIR > 0
+  #define X_HOME_TO_MAX 1
+#elif X_HOME_DIR < 0
+  #define X_HOME_TO_MIN 1
+#endif
+#if Y_HOME_DIR > 0
+  #define Y_HOME_TO_MAX 1
+#elif Y_HOME_DIR < 0
+  #define Y_HOME_TO_MIN 1
+#endif
+#if Z_HOME_DIR > 0
+  #define Z_HOME_TO_MAX 1
+#elif Z_HOME_DIR < 0
+  #define Z_HOME_TO_MIN 1
+#endif
+
 #if HAS_BED_PROBE
   #if DISABLED(NOZZLE_AS_PROBE)
     #define HAS_PROBE_XY_OFFSET 1
@@ -821,7 +838,7 @@
   #if DISABLED(Z_MIN_PROBE_USES_Z_MIN_ENDSTOP_PIN) && !BOTH(DELTA, SENSORLESS_PROBING)
     #define HAS_CUSTOM_PROBE_PIN 1
   #endif
-  #if Z_HOME_DIR < 0 && (!HAS_CUSTOM_PROBE_PIN || ENABLED(USE_PROBE_FOR_Z_HOMING))
+  #if Z_HOME_TO_MIN && (!HAS_CUSTOM_PROBE_PIN || ENABLED(USE_PROBE_FOR_Z_HOMING))
     #define HOMING_Z_WITH_PROBE 1
   #endif
   #ifndef Z_PROBE_LOW_POINT
@@ -843,7 +860,7 @@
   #undef USE_PROBE_FOR_Z_HOMING
 #endif
 
-#if Z_HOME_DIR > 0
+#if Z_HOME_TO_MAX
   #define HOME_Z_FIRST // If homing away from BED do Z first
 #endif
 
diff --git a/Marlin/src/inc/Conditionals_adv.h b/Marlin/src/inc/Conditionals_adv.h
index 44ea34a490..95a7ada83f 100644
--- a/Marlin/src/inc/Conditionals_adv.h
+++ b/Marlin/src/inc/Conditionals_adv.h
@@ -391,6 +391,12 @@
   #define POLL_JOG
 #endif
 
+#if X2_HOME_DIR > 0
+  #define X2_HOME_TO_MAX 1
+#elif X2_HOME_DIR < 0
+  #define X2_HOME_TO_MIN 1
+#endif
+
 #ifndef HOMING_BUMP_MM
   #define HOMING_BUMP_MM { 0, 0, 0 }
 #endif
diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index 46c1e59020..d86b02bdc2 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -155,7 +155,7 @@
 #ifdef MANUAL_X_HOME_POS
   #define X_HOME_POS MANUAL_X_HOME_POS
 #else
-  #define X_END_POS (X_HOME_DIR < 0 ? X_MIN_POS : X_MAX_POS)
+  #define X_END_POS TERN(X_HOME_TO_MIN, X_MIN_POS, X_MAX_POS)
   #if ENABLED(BED_CENTER_AT_0_0)
     #define X_HOME_POS TERN(DELTA, 0, X_END_POS)
   #else
@@ -166,7 +166,7 @@
 #ifdef MANUAL_Y_HOME_POS
   #define Y_HOME_POS MANUAL_Y_HOME_POS
 #else
-  #define Y_END_POS (Y_HOME_DIR < 0 ? Y_MIN_POS : Y_MAX_POS)
+  #define Y_END_POS TERN(Y_HOME_TO_MIN, Y_MIN_POS, Y_MAX_POS)
   #if ENABLED(BED_CENTER_AT_0_0)
     #define Y_HOME_POS TERN(DELTA, 0, Y_END_POS)
   #else
@@ -177,7 +177,7 @@
 #ifdef MANUAL_Z_HOME_POS
   #define Z_HOME_POS MANUAL_Z_HOME_POS
 #else
-  #define Z_HOME_POS (Z_HOME_DIR < 0 ? Z_MIN_POS : Z_MAX_POS)
+  #define Z_HOME_POS TERN(Z_HOME_TO_MIN, Z_MIN_POS, Z_MAX_POS)
 #endif
 
 /**
@@ -798,7 +798,7 @@
  * X_DUAL_ENDSTOPS endstop reassignment
  */
 #if ENABLED(X_DUAL_ENDSTOPS)
-  #if X_HOME_DIR > 0
+  #if X_HOME_TO_MAX
     #ifndef X2_MAX_ENDSTOP_INVERTING
       #if X2_USE_ENDSTOP == _XMIN_
         #define X2_MAX_ENDSTOP_INVERTING X_MIN_ENDSTOP_INVERTING
@@ -921,7 +921,7 @@
  * Y_DUAL_ENDSTOPS endstop reassignment
  */
 #if ENABLED(Y_DUAL_ENDSTOPS)
-  #if Y_HOME_DIR > 0
+  #if Y_HOME_TO_MAX
     #ifndef Y2_MAX_ENDSTOP_INVERTING
       #if Y2_USE_ENDSTOP == _XMIN_
         #define Y2_MAX_ENDSTOP_INVERTING X_MIN_ENDSTOP_INVERTING
@@ -1045,7 +1045,7 @@
  */
 #if ENABLED(Z_MULTI_ENDSTOPS)
 
-  #if Z_HOME_DIR > 0
+  #if Z_HOME_TO_MAX
     #ifndef Z2_MAX_ENDSTOP_INVERTING
       #if Z2_USE_ENDSTOP == _XMIN_
         #define Z2_MAX_ENDSTOP_INVERTING X_MIN_ENDSTOP_INVERTING
@@ -1164,7 +1164,7 @@
   #endif
 
   #if NUM_Z_STEPPER_DRIVERS >= 3
-    #if Z_HOME_DIR > 0
+    #if Z_HOME_TO_MAX
       #ifndef Z3_MAX_ENDSTOP_INVERTING
         #if Z3_USE_ENDSTOP == _XMIN_
           #define Z3_MAX_ENDSTOP_INVERTING X_MIN_ENDSTOP_INVERTING
@@ -1284,7 +1284,7 @@
   #endif
 
   #if NUM_Z_STEPPER_DRIVERS >= 4
-    #if Z_HOME_DIR > 0
+    #if Z_HOME_TO_MAX
       #ifndef Z4_MAX_ENDSTOP_INVERTING
         #if Z4_USE_ENDSTOP == _XMIN_
           #define Z4_MAX_ENDSTOP_INVERTING X_MIN_ENDSTOP_INVERTING
diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index 04f8a45c3b..b9eacd0a1a 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -1682,7 +1682,7 @@ static_assert(hbm[Z_AXIS] >= 0, "HOMING_BUMP_MM.Z must be greater than or equal
  * Allen Key
  * Deploying the Allen Key probe uses big moves in z direction. Too dangerous for an unhomed z-axis.
  */
-#if BOTH(Z_PROBE_ALLEN_KEY, Z_MIN_PROBE_USES_Z_MIN_ENDSTOP_PIN) && Z_HOME_DIR < 0
+#if ALL(Z_HOME_TO_MIN, Z_PROBE_ALLEN_KEY, Z_MIN_PROBE_USES_Z_MIN_ENDSTOP_PIN)
   #error "You can't home to a Z min endstop with a Z_PROBE_ALLEN_KEY."
 #endif
 
@@ -1700,7 +1700,7 @@ static_assert(hbm[Z_AXIS] >= 0, "HOMING_BUMP_MM.Z must be greater than or equal
     #error "DUAL_X_CARRIAGE requires USE_XMAX_PLUG and an X Max Endstop."
   #elif !defined(X2_HOME_POS) || !defined(X2_MIN_POS) || !defined(X2_MAX_POS)
     #error "DUAL_X_CARRIAGE requires X2_HOME_POS, X2_MIN_POS, and X2_MAX_POS."
-  #elif X_HOME_DIR != -1 || X2_HOME_DIR != 1
+  #elif X_HOME_TO_MAX || X2_HOME_TO_MIN
     #error "DUAL_X_CARRIAGE requires X_HOME_DIR -1 and X2_HOME_DIR 1."
   #endif
 #endif
@@ -2089,25 +2089,25 @@ static_assert(hbm[Z_AXIS] >= 0, "HOMING_BUMP_MM.Z must be greater than or equal
 
   // Delta and Cartesian use 3 homing endstops
   #if NONE(IS_SCARA, SPI_ENDSTOPS)
-    #if X_HOME_DIR < 0 && DISABLED(USE_XMIN_PLUG)
+    #if X_HOME_TO_MIN && DISABLED(USE_XMIN_PLUG)
       #error "Enable USE_XMIN_PLUG when homing X to MIN."
-    #elif X_HOME_DIR > 0 && DISABLED(USE_XMAX_PLUG)
+    #elif X_HOME_TO_MAX && DISABLED(USE_XMAX_PLUG)
       #error "Enable USE_XMAX_PLUG when homing X to MAX."
-    #elif Y_HOME_DIR < 0 && DISABLED(USE_YMIN_PLUG)
+    #elif Y_HOME_TO_MIN && DISABLED(USE_YMIN_PLUG)
       #error "Enable USE_YMIN_PLUG when homing Y to MIN."
-    #elif Y_HOME_DIR > 0 && DISABLED(USE_YMAX_PLUG)
+    #elif Y_HOME_TO_MAX && DISABLED(USE_YMAX_PLUG)
       #error "Enable USE_YMAX_PLUG when homing Y to MAX."
     #endif
   #endif
 
   // Z homing direction and plug usage flags
-  #if Z_HOME_DIR < 0 && NONE(USE_ZMIN_PLUG, HOMING_Z_WITH_PROBE)
+  #if Z_HOME_TO_MIN && NONE(USE_ZMIN_PLUG, HOMING_Z_WITH_PROBE)
     #error "Enable USE_ZMIN_PLUG when homing Z to MIN."
-  #elif Z_HOME_DIR > 0 && ENABLED(USE_PROBE_FOR_Z_HOMING)
+  #elif Z_HOME_TO_MAX && ENABLED(USE_PROBE_FOR_Z_HOMING)
     #error "Z_HOME_DIR must be -1 when homing Z with the probe."
   #elif BOTH(HOMING_Z_WITH_PROBE, Z_MULTI_ENDSTOPS)
     #error "Z_MULTI_ENDSTOPS is incompatible with USE_PROBE_FOR_Z_HOMING."
-  #elif Z_HOME_DIR > 0 && DISABLED(USE_ZMAX_PLUG)
+  #elif Z_HOME_TO_MAX && DISABLED(USE_ZMAX_PLUG)
     #error "Enable USE_ZMAX_PLUG when homing Z to MAX."
   #endif
 #endif
@@ -2630,17 +2630,17 @@ static_assert(hbm[Z_AXIS] >= 0, "HOMING_BUMP_MM.Z must be greater than or equal
   #define Z_ENDSTOP_INVERTING !AXIS_DRIVER_TYPE(Z,TMC2209)
 
   #if NONE(SPI_ENDSTOPS, ONBOARD_ENDSTOPPULLUPS, ENDSTOPPULLUPS)
-    #if   X_SENSORLESS && X_HOME_DIR < 0 && DISABLED(ENDSTOPPULLUP_XMIN)
+    #if   X_SENSORLESS && X_HOME_TO_MIN && DISABLED(ENDSTOPPULLUP_XMIN)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_XMIN (or ENDSTOPPULLUPS) when homing to X_MIN."
-    #elif X_SENSORLESS && X_HOME_DIR > 0 && DISABLED(ENDSTOPPULLUP_XMAX)
+    #elif X_SENSORLESS && X_HOME_TO_MAX && DISABLED(ENDSTOPPULLUP_XMAX)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_XMAX (or ENDSTOPPULLUPS) when homing to X_MAX."
-    #elif Y_SENSORLESS && Y_HOME_DIR < 0 && DISABLED(ENDSTOPPULLUP_YMIN)
+    #elif Y_SENSORLESS && Y_HOME_TO_MIN && DISABLED(ENDSTOPPULLUP_YMIN)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_YMIN (or ENDSTOPPULLUPS) when homing to Y_MIN."
-    #elif Y_SENSORLESS && Y_HOME_DIR > 0 && DISABLED(ENDSTOPPULLUP_YMAX)
+    #elif Y_SENSORLESS && Y_HOME_TO_MAX && DISABLED(ENDSTOPPULLUP_YMAX)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_YMAX (or ENDSTOPPULLUPS) when homing to Y_MAX."
-    #elif Z_SENSORLESS && Z_HOME_DIR < 0 && DISABLED(ENDSTOPPULLUP_ZMIN)
+    #elif Z_SENSORLESS && Z_HOME_TO_MIN && DISABLED(ENDSTOPPULLUP_ZMIN)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_ZMIN (or ENDSTOPPULLUPS) when homing to Z_MIN."
-    #elif Z_SENSORLESS && Z_HOME_DIR > 0 && DISABLED(ENDSTOPPULLUP_ZMAX)
+    #elif Z_SENSORLESS && Z_HOME_TO_MAX && DISABLED(ENDSTOPPULLUP_ZMAX)
       #error "SENSORLESS_HOMING requires ENDSTOPPULLUP_ZMAX (or ENDSTOPPULLUPS) when homing to Z_MAX."
     #endif
   #endif
@@ -2650,37 +2650,37 @@ static_assert(hbm[Z_AXIS] >= 0, "HOMING_BUMP_MM.Z must be greater than or equal
       #warning "SPI_ENDSTOPS may be unreliable with QUICK_HOME. Adjust back-offs for better results."
     #endif
   #else
-    #if X_SENSORLESS && X_HOME_DIR < 0 && X_MIN_ENDSTOP_INVERTING != X_ENDSTOP_INVERTING
+    #if X_SENSORLESS && X_HOME_TO_MIN && X_MIN_ENDSTOP_INVERTING != X_ENDSTOP_INVERTING
       #if X_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires X_MIN_ENDSTOP_INVERTING = true when homing to X_MIN."
       #else
         #error "SENSORLESS_HOMING requires X_MIN_ENDSTOP_INVERTING = false when homing TMC2209 to X_MIN."
       #endif
-    #elif X_SENSORLESS && X_HOME_DIR > 0 && X_MAX_ENDSTOP_INVERTING != X_ENDSTOP_INVERTING
+    #elif X_SENSORLESS && X_HOME_TO_MAX && X_MAX_ENDSTOP_INVERTING != X_ENDSTOP_INVERTING
       #if X_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires X_MAX_ENDSTOP_INVERTING = true when homing to X_MAX."
       #else
         #error "SENSORLESS_HOMING requires X_MAX_ENDSTOP_INVERTING = false when homing TMC2209 to X_MAX."
       #endif
-    #elif Y_SENSORLESS && Y_HOME_DIR < 0 && Y_MIN_ENDSTOP_INVERTING != Y_ENDSTOP_INVERTING
+    #elif Y_SENSORLESS && Y_HOME_TO_MIN && Y_MIN_ENDSTOP_INVERTING != Y_ENDSTOP_INVERTING
       #if Y_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires Y_MIN_ENDSTOP_INVERTING = true when homing to Y_MIN."
       #else
         #error "SENSORLESS_HOMING requires Y_MIN_ENDSTOP_INVERTING = false when homing TMC2209 to Y_MIN."
       #endif
-    #elif Y_SENSORLESS && Y_HOME_DIR > 0 && Y_MAX_ENDSTOP_INVERTING != Y_ENDSTOP_INVERTING
+    #elif Y_SENSORLESS && Y_HOME_TO_MAX && Y_MAX_ENDSTOP_INVERTING != Y_ENDSTOP_INVERTING
       #if Y_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires Y_MAX_ENDSTOP_INVERTING = true when homing to Y_MAX."
       #else
         #error "SENSORLESS_HOMING requires Y_MAX_ENDSTOP_INVERTING = false when homing TMC2209 to Y_MAX."
       #endif
-    #elif Z_SENSORLESS && Z_HOME_DIR < 0 && Z_MIN_ENDSTOP_INVERTING != Z_ENDSTOP_INVERTING
+    #elif Z_SENSORLESS && Z_HOME_TO_MIN && Z_MIN_ENDSTOP_INVERTING != Z_ENDSTOP_INVERTING
       #if Z_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires Z_MIN_ENDSTOP_INVERTING = true when homing to Z_MIN."
       #else
         #error "SENSORLESS_HOMING requires Z_MIN_ENDSTOP_INVERTING = false when homing TMC2209 to Z_MIN."
       #endif
-    #elif Z_SENSORLESS && Z_HOME_DIR > 0 && Z_MAX_ENDSTOP_INVERTING != Z_ENDSTOP_INVERTING
+    #elif Z_SENSORLESS && Z_HOME_TO_MAX && Z_MAX_ENDSTOP_INVERTING != Z_ENDSTOP_INVERTING
       #if Z_ENDSTOP_INVERTING
         #error "SENSORLESS_HOMING requires Z_MAX_ENDSTOP_INVERTING = true when homing to Z_MAX."
       #else
@@ -2918,9 +2918,9 @@ static_assert(   _ARR_TEST(3,0) && _ARR_TEST(3,1) && _ARR_TEST(3,2)
     #error "POWER_LOSS_RECOVER_ZHOME cannot be used with Z_SAFE_HOMING."
   #elif BOTH(POWER_LOSS_PULLUP, POWER_LOSS_PULLDOWN)
     #error "You can't enable POWER_LOSS_PULLUP and POWER_LOSS_PULLDOWN at the same time."
-  #elif ENABLED(POWER_LOSS_RECOVER_ZHOME) && Z_HOME_DIR > 0
+  #elif ENABLED(POWER_LOSS_RECOVER_ZHOME) && Z_HOME_TO_MAX
     #error "POWER_LOSS_RECOVER_ZHOME is not needed on a machine that homes to ZMAX."
-  #elif BOTH(IS_CARTESIAN, POWER_LOSS_RECOVER_ZHOME) && Z_HOME_DIR < 0 && !defined(POWER_LOSS_ZHOME_POS)
+  #elif BOTH(IS_CARTESIAN, POWER_LOSS_RECOVER_ZHOME) && Z_HOME_TO_MIN && !defined(POWER_LOSS_ZHOME_POS)
     #error "POWER_LOSS_RECOVER_ZHOME requires POWER_LOSS_ZHOME_POS for a Cartesian that homes to ZMIN."
   #endif
 #endif
diff --git a/Marlin/src/lcd/extui/ftdi_eve_touch_ui/screens/move_axis_screen.cpp b/Marlin/src/lcd/extui/ftdi_eve_touch_ui/screens/move_axis_screen.cpp
index 67ea002d34..9406572c33 100644
--- a/Marlin/src/lcd/extui/ftdi_eve_touch_ui/screens/move_axis_screen.cpp
+++ b/Marlin/src/lcd/extui/ftdi_eve_touch_ui/screens/move_axis_screen.cpp
@@ -66,7 +66,7 @@ void MoveAxisScreen::onRedraw(draw_mode_t what) {
       w.adjuster( 14, GET_TEXT_F(MSG_AXIS_E4), mydata.e_rel[3], canMove(E3));
     #endif
   #endif
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     w.button(24, GET_TEXT_F(MSG_MOVE_Z_TO_TOP), !axis_should_home(Z_AXIS));
   #endif
   w.increments();
diff --git a/Marlin/src/lcd/marlinui.cpp b/Marlin/src/lcd/marlinui.cpp
index acc3b63ac0..1d312535c9 100644
--- a/Marlin/src/lcd/marlinui.cpp
+++ b/Marlin/src/lcd/marlinui.cpp
@@ -488,12 +488,12 @@ bool MarlinUI::get_blink() {
 
           if (RRK(EN_KEYPAD_MIDDLE))  goto_screen(menu_move);
 
-          #if DISABLED(DELTA) && Z_HOME_DIR < 0
+          #if NONE(DELTA, Z_HOME_TO_MAX)
             if (RRK(EN_KEYPAD_F2))    _reprapworld_keypad_move(Z_AXIS,  1);
           #endif
 
           if (homed) {
-            #if ENABLED(DELTA) || Z_HOME_DIR != -1
+            #if EITHER(DELTA, Z_HOME_TO_MAX)
               if (RRK(EN_KEYPAD_F2))  _reprapworld_keypad_move(Z_AXIS,  1);
             #endif
             if (RRK(EN_KEYPAD_F3))    _reprapworld_keypad_move(Z_AXIS, -1);
diff --git a/Marlin/src/module/endstops.cpp b/Marlin/src/module/endstops.cpp
index d0befe71fb..7a452f1fdd 100644
--- a/Marlin/src/module/endstops.cpp
+++ b/Marlin/src/module/endstops.cpp
@@ -513,14 +513,8 @@ void Endstops::update() {
   #endif
 
   // With Dual X, endstops are only checked in the homing direction for the active extruder
-  #if ENABLED(DUAL_X_CARRIAGE)
-    #define E0_ACTIVE stepper.last_moved_extruder == 0
-    #define X_MIN_TEST() ((X_HOME_DIR < 0 && E0_ACTIVE) || (X2_HOME_DIR < 0 && !E0_ACTIVE))
-    #define X_MAX_TEST() ((X_HOME_DIR > 0 && E0_ACTIVE) || (X2_HOME_DIR > 0 && !E0_ACTIVE))
-  #else
-    #define X_MIN_TEST() true
-    #define X_MAX_TEST() true
-  #endif
+  #define X_MIN_TEST() TERN1(DUAL_X_CARRIAGE, TERN0(X_HOME_TO_MIN, stepper.last_moved_extruder == 0) || TERN0(X2_HOME_TO_MIN, stepper.last_moved_extruder != 0))
+  #define X_MAX_TEST() TERN1(DUAL_X_CARRIAGE, TERN0(X_HOME_TO_MAX, stepper.last_moved_extruder == 0) || TERN0(X2_HOME_TO_MAX, stepper.last_moved_extruder != 0))
 
   // Use HEAD for core axes, AXIS for others
   #if ANY(CORE_IS_XY, CORE_IS_XZ, MARKFORGED_XY)
@@ -765,7 +759,7 @@ void Endstops::update() {
 
   if (stepper.axis_is_moving(X_AXIS)) {
     if (stepper.motor_direction(X_AXIS_HEAD)) { // -direction
-      #if HAS_X_MIN || (X_SPI_SENSORLESS && X_HOME_DIR < 0)
+      #if HAS_X_MIN || (X_SPI_SENSORLESS && X_HOME_TO_MIN)
         PROCESS_ENDSTOP_X(MIN);
         #if   CORE_DIAG(XY, Y, MIN)
           PROCESS_CORE_ENDSTOP(Y,MIN,X,MIN);
@@ -779,7 +773,7 @@ void Endstops::update() {
       #endif
     }
     else { // +direction
-      #if HAS_X_MAX || (X_SPI_SENSORLESS && X_HOME_DIR > 0)
+      #if HAS_X_MAX || (X_SPI_SENSORLESS && X_HOME_TO_MAX)
         PROCESS_ENDSTOP_X(MAX);
         #if   CORE_DIAG(XY, Y, MIN)
           PROCESS_CORE_ENDSTOP(Y,MIN,X,MAX);
@@ -796,7 +790,7 @@ void Endstops::update() {
 
   if (stepper.axis_is_moving(Y_AXIS)) {
     if (stepper.motor_direction(Y_AXIS_HEAD)) { // -direction
-      #if HAS_Y_MIN || (Y_SPI_SENSORLESS && Y_HOME_DIR < 0)
+      #if HAS_Y_MIN || (Y_SPI_SENSORLESS && Y_HOME_TO_MIN)
         PROCESS_ENDSTOP_Y(MIN);
         #if   CORE_DIAG(XY, X, MIN)
           PROCESS_CORE_ENDSTOP(X,MIN,Y,MIN);
@@ -810,7 +804,7 @@ void Endstops::update() {
       #endif
     }
     else { // +direction
-      #if HAS_Y_MAX || (Y_SPI_SENSORLESS && Y_HOME_DIR > 0)
+      #if HAS_Y_MAX || (Y_SPI_SENSORLESS && Y_HOME_TO_MAX)
         PROCESS_ENDSTOP_Y(MAX);
         #if   CORE_DIAG(XY, X, MIN)
           PROCESS_CORE_ENDSTOP(X,MIN,Y,MAX);
@@ -828,7 +822,7 @@ void Endstops::update() {
   if (stepper.axis_is_moving(Z_AXIS)) {
     if (stepper.motor_direction(Z_AXIS_HEAD)) { // Z -direction. Gantry down, bed up.
 
-      #if HAS_Z_MIN || (Z_SPI_SENSORLESS && Z_HOME_DIR < 0)
+      #if HAS_Z_MIN || (Z_SPI_SENSORLESS && Z_HOME_TO_MIN)
         if ( TERN1(Z_MIN_PROBE_USES_Z_MIN_ENDSTOP_PIN, z_probe_enabled)
           && TERN1(HAS_CUSTOM_PROBE_PIN, !z_probe_enabled)
         ) PROCESS_ENDSTOP_Z(MIN);
@@ -849,7 +843,7 @@ void Endstops::update() {
       #endif
     }
     else { // Z +direction. Gantry up, bed down.
-      #if HAS_Z_MAX || (Z_SPI_SENSORLESS && Z_HOME_DIR > 0)
+      #if HAS_Z_MAX || (Z_SPI_SENSORLESS && Z_HOME_TO_MAX)
         #if ENABLED(Z_MULTI_ENDSTOPS)
           PROCESS_ENDSTOP_Z(MAX);
         #elif !HAS_CUSTOM_PROBE_PIN || Z_MAX_PIN != Z_MIN_PROBE_PIN  // No probe or probe is Z_MIN || Probe is not Z_MAX
diff --git a/Marlin/src/module/endstops.h b/Marlin/src/module/endstops.h
index 7d18aaf850..acd241d432 100644
--- a/Marlin/src/module/endstops.h
+++ b/Marlin/src/module/endstops.h
@@ -62,9 +62,9 @@ enum EndstopEnum : char {
   NUM_ENDSTOP_STATES
 };
 
-#define X_ENDSTOP (x_home_dir(active_extruder) < 0 ? X_MIN : X_MAX)
-#define Y_ENDSTOP (Y_HOME_DIR < 0 ? Y_MIN : Y_MAX)
-#define Z_ENDSTOP (Z_HOME_DIR < 0 ? TERN(HOMING_Z_WITH_PROBE, Z_MIN, Z_MIN_PROBE) : Z_MAX)
+#define X_ENDSTOP TERN(X_HOME_TO_MAX, X_MAX, X_MIN)
+#define Y_ENDSTOP TERN(Y_HOME_TO_MAX, Y_MAX, Y_MIN)
+#define Z_ENDSTOP TERN(Z_HOME_TO_MAX, Z_MAX, TERN(HOMING_Z_WITH_PROBE, Z_MIN, Z_MIN_PROBE))
 
 #undef __ES_ITEM
 #undef _ES_ITEM
diff --git a/Marlin/src/module/motion.cpp b/Marlin/src/module/motion.cpp
index 52d9dec904..69aed1e192 100644
--- a/Marlin/src/module/motion.cpp
+++ b/Marlin/src/module/motion.cpp
@@ -1378,7 +1378,7 @@ void prepare_line_to_destination() {
 
     // Only do some things when moving towards an endstop
     const int8_t axis_home_dir = TERN0(DUAL_X_CARRIAGE, axis == X_AXIS)
-                  ? x_home_dir(active_extruder) : home_dir(axis);
+                  ? TOOL_X_HOME_DIR(active_extruder) : home_dir(axis);
     const bool is_home_dir = (axis_home_dir > 0) == (distance > 0);
 
     #if ENABLED(SENSORLESS_HOMING)
@@ -1562,8 +1562,8 @@ void prepare_line_to_destination() {
       #define _CAN_HOME(A) (axis == _AXIS(A) && ( \
            ENABLED(A##_SPI_SENSORLESS) \
         || (_AXIS(A) == Z_AXIS && ENABLED(HOMING_Z_WITH_PROBE)) \
-        || (A##_MIN_PIN > -1 && A##_HOME_DIR < 0) \
-        || (A##_MAX_PIN > -1 && A##_HOME_DIR > 0) \
+        || TERN0(A##_HOME_TO_MIN, A##_MIN_PIN > -1) \
+        || TERN0(A##_HOME_TO_MAX, A##_MAX_PIN > -1) \
       ))
       if (!_CAN_HOME(X) && !_CAN_HOME(Y) && !_CAN_HOME(Z)) return;
     #endif
@@ -1571,7 +1571,7 @@ void prepare_line_to_destination() {
     if (DEBUGGING(LEVELING)) DEBUG_ECHOLNPAIR(">>> homeaxis(", AS_CHAR(axis_codes[axis]), ")");
 
     const int axis_home_dir = TERN0(DUAL_X_CARRIAGE, axis == X_AXIS)
-                ? x_home_dir(active_extruder) : home_dir(axis);
+                ? TOOL_X_HOME_DIR(active_extruder) : home_dir(axis);
 
     //
     // Homing Z with a probe? Raise Z (maybe) and deploy the Z probe.
@@ -1916,7 +1916,7 @@ void set_axis_is_at_home(const AxisEnum axis) {
   /**
    * Z Probe Z Homing? Account for the probe's Z offset.
    */
-  #if HAS_BED_PROBE && Z_HOME_DIR < 0
+  #if HAS_BED_PROBE && Z_HOME_TO_MIN
     if (axis == Z_AXIS) {
       #if HOMING_Z_WITH_PROBE
 
diff --git a/Marlin/src/module/motion.h b/Marlin/src/module/motion.h
index 15713e6d4d..3c6f044b21 100644
--- a/Marlin/src/module/motion.h
+++ b/Marlin/src/module/motion.h
@@ -517,7 +517,7 @@ FORCE_INLINE bool all_axes_trusted()                        { return linear_bits
 
   float x_home_pos(const uint8_t extruder);
 
-  FORCE_INLINE int x_home_dir(const uint8_t extruder) { return extruder ? X2_HOME_DIR : X_HOME_DIR; }
+  #define TOOL_X_HOME_DIR(T) ((T) ? X2_HOME_DIR : X_HOME_DIR)
 
   void set_duplication_enabled(const bool dupe, const int8_t tool_index=-1);
   void idex_set_mirrored_mode(const bool mirr);
@@ -531,7 +531,7 @@ FORCE_INLINE bool all_axes_trusted()                        { return linear_bits
     FORCE_INLINE void set_duplication_enabled(const bool dupe) { extruder_duplication_enabled = dupe; }
   #endif
 
-  FORCE_INLINE int x_home_dir(const uint8_t) { return X_HOME_DIR; }
+  #define TOOL_X_HOME_DIR(T) X_HOME_DIR
 
 #endif
 
diff --git a/Marlin/src/module/scara.cpp b/Marlin/src/module/scara.cpp
index b0544c7791..07f714a997 100644
--- a/Marlin/src/module/scara.cpp
+++ b/Marlin/src/module/scara.cpp
@@ -221,10 +221,10 @@ float segments_per_second = TERN(AXEL_TPARA, TPARA_SEGMENTS_PER_SECOND, SCARA_SE
       TERN_(Z_SENSORLESS, sensorless_t stealth_states_z = start_sensorless_homing_per_axis(Z_AXIS));
     #endif
 
-    // const int x_axis_home_dir = x_home_dir(active_extruder);
+    //const int x_axis_home_dir = TOOL_X_HOME_DIR(active_extruder);
 
-    // const xy_pos_t pos { max_length(X_AXIS) , max_length(Y_AXIS) };
-    // const float mlz = max_length(X_AXIS),
+    //const xy_pos_t pos { max_length(X_AXIS) , max_length(Y_AXIS) };
+    //const float mlz = max_length(X_AXIS),
 
     // Move all carriages together linearly until an endstop is hit.
     //do_blocking_move_to_xy_z(pos, mlz, homing_feedrate(Z_AXIS));
diff --git a/Marlin/src/module/stepper.cpp b/Marlin/src/module/stepper.cpp
index e8f578ae91..2e2afaeb90 100644
--- a/Marlin/src/module/stepper.cpp
+++ b/Marlin/src/module/stepper.cpp
@@ -259,7 +259,7 @@ xyze_int8_t Stepper::count_direction{0};
 
 #define DUAL_ENDSTOP_APPLY_STEP(A,V)                                                                                        \
   if (separate_multi_axis) {                                                                                                \
-    if (A##_HOME_DIR < 0) {                                                                                                 \
+    if (A##_HOME_TO_MIN) {                                                                                                  \
       if (TERN0(HAS_##A##_MIN, !(TEST(endstops.state(), A##_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##_motor)) A##_STEP_WRITE(V);     \
       if (TERN0(HAS_##A##2_MIN, !(TEST(endstops.state(), A##2_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##2_motor)) A##2_STEP_WRITE(V); \
     }                                                                                                                       \
@@ -285,7 +285,7 @@ xyze_int8_t Stepper::count_direction{0};
 
 #define TRIPLE_ENDSTOP_APPLY_STEP(A,V)                                                                                      \
   if (separate_multi_axis) {                                                                                                \
-    if (A##_HOME_DIR < 0) {                                                                                                 \
+    if (A##_HOME_TO_MIN) {                                                                                                  \
       if (!(TEST(endstops.state(), A##_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##_motor) A##_STEP_WRITE(V);    \
       if (!(TEST(endstops.state(), A##2_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##2_motor) A##2_STEP_WRITE(V); \
       if (!(TEST(endstops.state(), A##3_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##3_motor) A##3_STEP_WRITE(V); \
@@ -316,7 +316,7 @@ xyze_int8_t Stepper::count_direction{0};
 
 #define QUAD_ENDSTOP_APPLY_STEP(A,V)                                                                                        \
   if (separate_multi_axis) {                                                                                                \
-    if (A##_HOME_DIR < 0) {                                                                                                 \
+    if (A##_HOME_TO_MIN) {                                                                                                  \
       if (!(TEST(endstops.state(), A##_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##_motor) A##_STEP_WRITE(V);    \
       if (!(TEST(endstops.state(), A##2_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##2_motor) A##2_STEP_WRITE(V); \
       if (!(TEST(endstops.state(), A##3_MIN) && count_direction[_AXIS(A)] < 0) && !locked_##A##3_motor) A##3_STEP_WRITE(V); \
diff --git a/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_3.h b/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_3.h
index 625de05996..b262212b7e 100644
--- a/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_3.h
+++ b/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_3.h
@@ -38,7 +38,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                      P1_28  // X+
   #else
     #define X_MIN_PIN                      P1_28  // X+
@@ -50,7 +50,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                      P1_26  // Y+
   #else
     #define Y_MIN_PIN                      P1_26  // Y+
@@ -62,7 +62,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                      P1_24  // Z+
   #else
     #define Z_MIN_PIN                      P1_24  // Z+
diff --git a/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_4.h b/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_4.h
index ba60db472e..0508c5b5a9 100644
--- a/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_4.h
+++ b/Marlin/src/pins/lpc1768/pins_BTT_SKR_V1_4.h
@@ -50,7 +50,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                      P1_26  // E0DET
   #else
     #define X_MIN_PIN                      P1_26  // E0DET
@@ -68,7 +68,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                      P1_25  // E1DET
   #else
     #define Y_MIN_PIN                      P1_25  // E1DET
@@ -86,7 +86,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                      P1_00  // PWRDET
   #else
     #define Z_MIN_PIN                      P1_00  // PWRDET
diff --git a/Marlin/src/pins/lpc1768/pins_MKS_SGEN_L.h b/Marlin/src/pins/lpc1768/pins_MKS_SGEN_L.h
index 40fac4e7fa..f998ecde4e 100644
--- a/Marlin/src/pins/lpc1768/pins_MKS_SGEN_L.h
+++ b/Marlin/src/pins/lpc1768/pins_MKS_SGEN_L.h
@@ -50,7 +50,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                      P1_28  // X+
   #else
     #define X_MIN_PIN                      P1_28  // X+
@@ -62,7 +62,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                      P1_26  // Y+
   #else
     #define Y_MIN_PIN                      P1_26  // Y+
@@ -74,7 +74,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                      P1_24  // Z+
   #else
     #define Z_MIN_PIN                      P1_24  // Z+
diff --git a/Marlin/src/pins/lpc1769/pins_MKS_SGEN_L_V2.h b/Marlin/src/pins/lpc1769/pins_MKS_SGEN_L_V2.h
index a616079403..1057147498 100644
--- a/Marlin/src/pins/lpc1769/pins_MKS_SGEN_L_V2.h
+++ b/Marlin/src/pins/lpc1769/pins_MKS_SGEN_L_V2.h
@@ -60,7 +60,7 @@
 //
 #if X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                      P1_28  // X+
   #else
     #define X_MIN_PIN                      P1_28  // X+
@@ -72,7 +72,7 @@
 
 #if Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                      P1_26  // Y+
   #else
     #define Y_MIN_PIN                      P1_26  // Y+
@@ -84,7 +84,7 @@
 
 #if Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                      P1_24  // Z+
   #else
     #define Z_MIN_PIN                      P1_24  // Z+
diff --git a/Marlin/src/pins/pins_postprocess.h b/Marlin/src/pins/pins_postprocess.h
index d71b79ca95..37ebbd47ad 100644
--- a/Marlin/src/pins/pins_postprocess.h
+++ b/Marlin/src/pins/pins_postprocess.h
@@ -385,7 +385,7 @@
 // Assign endstop pins for boards with only 3 connectors
 //
 #ifdef X_STOP_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MIN_PIN X_STOP_PIN
     #ifndef X_MAX_PIN
       #define X_MAX_PIN -1
@@ -396,14 +396,14 @@
       #define X_MIN_PIN -1
     #endif
   #endif
-#elif X_HOME_DIR < 0
+#elif X_HOME_TO_MIN
   #define X_STOP_PIN X_MIN_PIN
 #else
   #define X_STOP_PIN X_MAX_PIN
 #endif
 
 #ifdef Y_STOP_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MIN_PIN Y_STOP_PIN
     #ifndef Y_MAX_PIN
       #define Y_MAX_PIN -1
@@ -414,14 +414,14 @@
       #define Y_MIN_PIN -1
     #endif
   #endif
-#elif Y_HOME_DIR < 0
+#elif Y_HOME_TO_MIN
   #define Y_STOP_PIN Y_MIN_PIN
 #else
   #define Y_STOP_PIN Y_MAX_PIN
 #endif
 
 #ifdef Z_STOP_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MIN_PIN Z_STOP_PIN
     #ifndef Z_MAX_PIN
       #define Z_MAX_PIN -1
@@ -432,7 +432,7 @@
       #define Z_MIN_PIN -1
     #endif
   #endif
-#elif Z_HOME_DIR < 0
+#elif Z_HOME_TO_MIN
   #define Z_STOP_PIN Z_MIN_PIN
 #else
   #define Z_STOP_PIN Z_MAX_PIN
@@ -489,34 +489,34 @@
   #undef Z_MIN_PIN
   #define Z_MIN_PIN          -1
 #endif
-#if DISABLED(X_DUAL_ENDSTOPS) || X_HOME_DIR > 0
+#if DISABLED(X_DUAL_ENDSTOPS) || X_HOME_TO_MAX
   #undef X2_MIN_PIN
 #endif
-#if DISABLED(X_DUAL_ENDSTOPS) || X_HOME_DIR < 0
+#if DISABLED(X_DUAL_ENDSTOPS) || X_HOME_TO_MIN
   #undef X2_MAX_PIN
 #endif
-#if DISABLED(Y_DUAL_ENDSTOPS) || Y_HOME_DIR > 0
+#if DISABLED(Y_DUAL_ENDSTOPS) || Y_HOME_TO_MAX
   #undef Y2_MIN_PIN
 #endif
-#if DISABLED(Y_DUAL_ENDSTOPS) || Y_HOME_DIR < 0
+#if DISABLED(Y_DUAL_ENDSTOPS) || Y_HOME_TO_MIN
   #undef Y2_MAX_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || Z_HOME_DIR > 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || Z_HOME_TO_MAX
   #undef Z2_MIN_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || Z_HOME_DIR < 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || Z_HOME_TO_MIN
   #undef Z2_MAX_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 3 || Z_HOME_DIR > 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 3 || Z_HOME_TO_MAX
   #undef Z3_MIN_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 3 || Z_HOME_DIR < 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 3 || Z_HOME_TO_MIN
   #undef Z3_MAX_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 4 || Z_HOME_DIR > 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 4 || Z_HOME_TO_MAX
   #undef Z4_MIN_PIN
 #endif
-#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 4 || Z_HOME_DIR < 0
+#if DISABLED(Z_MULTI_ENDSTOPS) || NUM_Z_STEPPER_DRIVERS < 4 || Z_HOME_TO_MIN
   #undef Z4_MAX_PIN
 #endif
 
diff --git a/Marlin/src/pins/rambo/pins_EINSY_RETRO.h b/Marlin/src/pins/rambo/pins_EINSY_RETRO.h
index ee537495ea..0c072745d5 100644
--- a/Marlin/src/pins/rambo/pins_EINSY_RETRO.h
+++ b/Marlin/src/pins/rambo/pins_EINSY_RETRO.h
@@ -61,7 +61,7 @@
 
 #else
 
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MIN_PIN                 X_DIAG_PIN
     #define X_MAX_PIN                         81  // X+
   #else
@@ -69,7 +69,7 @@
     #define X_MAX_PIN                 X_DIAG_PIN
   #endif
 
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MIN_PIN                 Y_DIAG_PIN
     #define Y_MAX_PIN                         57  // Y+
   #else
diff --git a/Marlin/src/pins/sam/pins_ARCHIM2.h b/Marlin/src/pins/sam/pins_ARCHIM2.h
index 3776cf8bb5..ecff888ff0 100644
--- a/Marlin/src/pins/sam/pins_ARCHIM2.h
+++ b/Marlin/src/pins/sam/pins_ARCHIM2.h
@@ -71,7 +71,7 @@
   #define E0_DIAG_PIN                         78  // PB23
   #define E1_DIAG_PIN                         25  // PD0
 
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MIN_PIN                 X_DIAG_PIN
     #define X_MAX_PIN                         32
   #else
@@ -79,7 +79,7 @@
     #define X_MAX_PIN                 X_DIAG_PIN
   #endif
 
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MIN_PIN                 Y_DIAG_PIN
     #define Y_MAX_PIN                         15
   #else
diff --git a/Marlin/src/pins/stm32f4/pins_BTT_E3_RRF.h b/Marlin/src/pins/stm32f4/pins_BTT_E3_RRF.h
index f808278510..621b136e17 100644
--- a/Marlin/src/pins/stm32f4/pins_BTT_E3_RRF.h
+++ b/Marlin/src/pins/stm32f4/pins_BTT_E3_RRF.h
@@ -55,7 +55,7 @@
   #define X2_DIR_PIN                   FPC10_PIN  // X2DIR
   #define X2_SERIAL_TX_PIN             FPC12_PIN  // X2UART
   #define X2_SERIAL_RX_PIN             FPC12_PIN  // X2UART
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                   FPC2_PIN  // X2-STOP
   #else
     #define X_MIN_PIN                   FPC2_PIN  // X2-STOP
diff --git a/Marlin/src/pins/stm32f4/pins_BTT_GTR_V1_0.h b/Marlin/src/pins/stm32f4/pins_BTT_GTR_V1_0.h
index 70d502f68a..70ac9a13c3 100644
--- a/Marlin/src/pins/stm32f4/pins_BTT_GTR_V1_0.h
+++ b/Marlin/src/pins/stm32f4/pins_BTT_GTR_V1_0.h
@@ -69,7 +69,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                E0_DIAG_PIN  // X+
   #else
     #define X_MIN_PIN                E0_DIAG_PIN  // X+
@@ -81,7 +81,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                E1_DIAG_PIN  // Y+
   #else
     #define Y_MIN_PIN                E1_DIAG_PIN  // Y+
@@ -93,7 +93,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                E2_DIAG_PIN  // Z+
   #else
     #define Z_MIN_PIN                E2_DIAG_PIN  // Z+
diff --git a/Marlin/src/pins/stm32f4/pins_BTT_OCTOPUS_V1_0.h b/Marlin/src/pins/stm32f4/pins_BTT_OCTOPUS_V1_0.h
index 6de3c544d3..34fe1a824b 100644
--- a/Marlin/src/pins/stm32f4/pins_BTT_OCTOPUS_V1_0.h
+++ b/Marlin/src/pins/stm32f4/pins_BTT_OCTOPUS_V1_0.h
@@ -71,7 +71,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                E0_DIAG_PIN  // E0DET
   #else
     #define X_MIN_PIN                E0_DIAG_PIN  // E0DET
@@ -89,7 +89,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                E1_DIAG_PIN  // E1DET
   #else
     #define Y_MIN_PIN                E1_DIAG_PIN  // E1DET
@@ -107,7 +107,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                E2_DIAG_PIN  // PWRDET
   #else
     #define Z_MIN_PIN                E2_DIAG_PIN  // PWRDET
diff --git a/Marlin/src/pins/stm32f4/pins_BTT_SKR_PRO_common.h b/Marlin/src/pins/stm32f4/pins_BTT_SKR_PRO_common.h
index 67907affa7..fe6d8740bd 100644
--- a/Marlin/src/pins/stm32f4/pins_BTT_SKR_PRO_common.h
+++ b/Marlin/src/pins/stm32f4/pins_BTT_SKR_PRO_common.h
@@ -71,7 +71,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                       PE15  // E0
   #else
     #define X_MIN_PIN                       PE15  // E0
@@ -83,7 +83,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                       PE10  // E1
   #else
     #define Y_MIN_PIN                       PE10  // E1
@@ -95,7 +95,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                       PG5   // E2
   #else
     #define Z_MIN_PIN                       PG5   // E2
diff --git a/Marlin/src/pins/stm32f4/pins_BTT_SKR_V2_0_common.h b/Marlin/src/pins/stm32f4/pins_BTT_SKR_V2_0_common.h
index a69041e2d4..5e2f88190d 100644
--- a/Marlin/src/pins/stm32f4/pins_BTT_SKR_V2_0_common.h
+++ b/Marlin/src/pins/stm32f4/pins_BTT_SKR_V2_0_common.h
@@ -72,7 +72,7 @@
 //
 #ifdef X_STALL_SENSITIVITY
   #define X_STOP_PIN                  X_DIAG_PIN
-  #if X_HOME_DIR < 0
+  #if X_HOME_TO_MIN
     #define X_MAX_PIN                       PC2   // E0DET
   #else
     #define X_MIN_PIN                       PC2   // E0DET
@@ -90,7 +90,7 @@
 
 #ifdef Y_STALL_SENSITIVITY
   #define Y_STOP_PIN                  Y_DIAG_PIN
-  #if Y_HOME_DIR < 0
+  #if Y_HOME_TO_MIN
     #define Y_MAX_PIN                       PA0   // E1DET
   #else
     #define Y_MIN_PIN                       PA0   // E1DET
@@ -108,7 +108,7 @@
 
 #ifdef Z_STALL_SENSITIVITY
   #define Z_STOP_PIN                  Z_DIAG_PIN
-  #if Z_HOME_DIR < 0
+  #if Z_HOME_TO_MIN
     #define Z_MAX_PIN                       PC15  // PWRDET
   #else
     #define Z_MIN_PIN                       PC15  // PWRDET