diff --git a/Marlin/src/HAL/SAMD21/u8g/u8g_com_HAL_samd21_shared_hw_spi.cpp b/Marlin/src/HAL/SAMD21/u8g/u8g_com_HAL_samd21_shared_hw_spi.cpp
index 02dc772296..025e5a3bb6 100644
--- a/Marlin/src/HAL/SAMD21/u8g/u8g_com_HAL_samd21_shared_hw_spi.cpp
+++ b/Marlin/src/HAL/SAMD21/u8g/u8g_com_HAL_samd21_shared_hw_spi.cpp
@@ -60,6 +60,10 @@
 
 #ifdef __SAMD21__
 
+#include "../../../inc/MarlinConfigPre.h"
+
+#if HAS_MARLINUI_U8GLIB
+
 #include <U8glib-HAL.h>
 #include "SPI.h"
 
@@ -151,4 +155,6 @@ uint8_t u8g_com_samd21_st7920_hw_spi_fn(u8g_t *u8g, uint8_t msg, uint8_t arg_val
   return 1;
 }
 
+#endif // HAS_MARLINUI_U8GLIB
+
 #endif // __SAMD21__