diff --git a/Marlin/Max7219_Debug_LEDs.cpp b/Marlin/Max7219_Debug_LEDs.cpp
index b185454c3d1..097baa05be1 100644
--- a/Marlin/Max7219_Debug_LEDs.cpp
+++ b/Marlin/Max7219_Debug_LEDs.cpp
@@ -410,22 +410,38 @@ void Max7219_init() {
 
 // Apply changes to update a marker
 inline void Max7219_Mark16(const uint8_t y, const uint8_t v1, const uint8_t v2) {
-  Max7219_LED_Off(v1 & 0x7, y + (v1 >= 8));
-   Max7219_LED_On(v2 & 0x7, y + (v2 >= 8));
+  #if MAX7219_X_LEDS == 8
+    Max7219_LED_Off(v1 & 0x7, y + (v1 >= 8));
+     Max7219_LED_On(v2 & 0x7, y + (v2 >= 8));
+  #else   // LED matrix has at least 16 LED's on the X-Axis.  Use single line of LED's
+    Max7219_LED_Off(v1 & 0xf, y);
+     Max7219_LED_On(v2 & 0xf, y);
+  #endif
 }
 
 // Apply changes to update a tail-to-head range
 inline void Max7219_Range16(const uint8_t y, const uint8_t ot, const uint8_t nt, const uint8_t oh, const uint8_t nh) {
-  if (ot != nt) for (uint8_t n = ot & 0xF; n != (nt & 0xF) && n != (nh & 0xF); n = (n + 1) & 0xF)
-    Max7219_LED_Off(n & 0x7, y + (n >= 8));
-  if (oh != nh) for (uint8_t n = (oh + 1) & 0xF; n != ((nh + 1) & 0xF); n = (n + 1) & 0xF)
-     Max7219_LED_On(n & 0x7, y + (n >= 8));
+  #if MAX7219_X_LEDS == 8
+    if (ot != nt) for (uint8_t n = ot & 0xF; n != (nt & 0xF) && n != (nh & 0xF); n = (n + 1) & 0xF)
+      Max7219_LED_Off(n & 0x7, y + (n >= 8));
+    if (oh != nh) for (uint8_t n = (oh + 1) & 0xF; n != ((nh + 1) & 0xF); n = (n + 1) & 0xF)
+       Max7219_LED_On(n & 0x7, y + (n >= 8));
+  #else   // LED matrix has at least 16 LED's on the X-Axis.  Use single line of LED's
+    if (ot != nt) for (uint8_t n = ot & 0xF; n != (nt & 0xF) && n != (nh & 0xF); n = (n + 1) & 0xF)
+      Max7219_LED_Off(n & 0xf, y);
+    if (oh != nh) for (uint8_t n = (oh + 1) & 0xF; n != ((nh + 1) & 0xF); n = (n + 1) & 0xF)
+       Max7219_LED_On(n & 0xf, y);
+ #endif
 }
 
 // Apply changes to update a quantity
 inline void Max7219_Quantity16(const uint8_t y, const uint8_t ov, const uint8_t nv) {
   for (uint8_t i = MIN(nv, ov); i < MAX(nv, ov); i++)
-    Max7219_LED_Set(i >> 1, y + (i & 1), nv >= ov);
+    #if MAX7219_X_LEDS == 8
+      Max7219_LED_Set(i >> 1, y + (i & 1), nv >= ov); // single 8x8 LED matrix.  Use two lines to get 16 LED's
+    #else
+      Max7219_LED_Set(i, y, nv >= ov);                // LED matrix has at least 16 LED's on the X-Axis.  Use single line of LED's
+    #endif
 }
 
 void Max7219_idle_tasks() {