diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 461101368ed..26595f93fed 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -1467,7 +1467,7 @@
  * A lightweight, solenoid-driven probe.
  * For information about this sensor https://github.com/bigtreetech/MicroProbe
  *
- * Also requires: PROBE_ENABLE_DISABLE
+ * Also requires: PROBE_ENABLE_DISABLE, ENDSTOP_INTERRUPTS_FEATURE if FT_MOTION is enabled.
  */
 //#define BIQU_MICROPROBE_V1  // Triggers HIGH
 //#define BIQU_MICROPROBE_V2  // Triggers LOW
diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index e733f87e4e8..59317002b03 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -1389,6 +1389,10 @@ static_assert(NUM_SERVOS <= NUM_SERVO_PLUGS, "NUM_SERVOS (or some servo index) i
       #error "BIQU MicroProbe requires a PROBE_ENABLE_PIN."
     #endif
 
+    #if ENABLED(FT_MOTION) && DISABLED(ENDSTOP_INTERRUPTS_FEATURE)
+      #error "BIQU Microprobe requires ENDSTOP_INTERRUPTS_FEATURE with FT_MOTION."
+    #endif
+
     #if ENABLED(BIQU_MICROPROBE_V1)
       #if ENABLED(INVERTED_PROBE_STATE)
         #if Z_MIN_PROBE_ENDSTOP_HIT_STATE != LOW